Dr. Alexey Rakov received a medical graduation from the Vladivostok State Medical University, where he received therapeutical speciality. He defined the correlation between plasmid profile of Salmonella enteritidis and clinical manifestation of Salmonella infection to earn his M.D. and Ph.D. at Institute of Epidemiology and Microbiology of Siberian Branch of Russian Academy of Medical Sciences in the lab of Dr. Felix Shubin (Laboratory of Molecular Epidemiology). Also he carried out the research of corellation between presence of virulence plasmids in Salmonella enteritidis and clinical manifestation of Salmonella infection.

Research in Dr. Rakov's lab revolves around the idea that a greater understanding of clonal organization will provide novel insights into host-pathogen interactions. This information will help us develop effective tools for diagnosing infectious diseases and help us design therapeutic strategies that favor quality outcomes for infected hosts. Salmonella infections can cause severe forms, and studying this system provides an excellent opportunity to understand: 1) clonal organization of genus Salmonella; 2) how virulent bacteria can cause extraintestinal Salmonella infection; 3) the correlations between plasmid profile and clinical manifestation of Salmonella infection; 4) the role of virulence plasmids in pathogenicity and clinics of infections caused by pathogens like Salmonella and Yersinia. In the course of these studies, the Rakov's lab uses techniques in molecular epidemiology, microbiology, and molecular biology (Salmonella monitoring, plasmid profile analysis, PCR, RAPD, PFGE etc.).

Searching opportunities for collaboration, grants, fellowships, trainings, schools, conferences on medical microbiology, molecular epidemiology, molecular biology, infectious diseases, etc.

You can email Dr. Rakov at (delete "nospam" before): nospam.vokar@mail333.com

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Representative publications from Dr. Rakov's lab (complete list here):

For detailed information about publications, please see:

Rakov A.V., Shubin F.N., Ivanis V.A., Kuznetsova N.A., Kovalchuk N.I., Revina V.V., Kosheleva N.G., Grebenkova L.K. Comparative characterization of infections caused by different plasmid profiles of Salmonella enteritidis. Epidemiology and Infectious Diseases (Moscow) 2001, No. 5, P. 50-54. [russian PDF] (695 kb) [english translation PDF] (242 kb) [abstract not avaliable] (indexed in Ulrich's International Periodical Directory)

Shubin F.N., Kovalchuk N.I., Kuznetsova N.A., Revina G.V., Rakov A.V., Belogolovkina N.A., Nechuhaeva E.M. Microbiological monitoring of Salmonella enteritidis strains in Primorye Region. Phenotypical and plasmid characterization of pathogen. Epidemiology and Infectious Diseases (Moscow) 2002, No. 1, P. 36-40. [russian PDF] (1,686 kb) [english translation PDF] (650 kb) [english abstract] [russian abstract] (indexed in Ulrich's International Periodical Directory)

Rakov A.V., Shubin F.N., Ivanis V.A., Kuznetsova N.A. Clinical & microbiological features of Salmonella infection caused by S. Enterica subsp. Enterica serovar enteritidis strains with different plasmid profiles. Abstracts of the 11th Australian Food Microbiology Conference, 28 March, 2003. Australia, 2003. [english HTML]

Rakov A.V., Shubin F.N., Ivanis V.A. Clinics of the infection caused by S. Enterica subsp. Enterica serovar enteritidis which is not containing virulence plasmids. Abstracts of the 11th Australian Food Microbiology Conference, 28 March, 2003. Australia, 2003. [english HTML]

Rakov A.V. Microbiological and clinical parallels of Salmonella infection. Author's Abstract. Vladivostok, 2003. [russian PDF] (423 kb)

Rakov A.V. Microbiological and clinical parallels of Salmonella infection. M.D.Ph.D. Thesis. Vladivostok, 2003. [russian zipped PDF] (2,929 kb)

Rakov A.V., Shubin F.N., Ivanis V.A. Microbiological and clinical characterization of extraintestinal Salmonella infection. Abstracts of the ASM Conference on Salmonella: Pathogenesis, Epidemiology, and Vaccine Development, September 20 - 24, 2003, Alghero, Sardinia, Italy, 2003, P. 38-39. [PDF] (603 kb)

Rakov A.V., Shubin F.N., Kuznetsova N.A., Ivanis V.A., Shklyar G.M. Microbiological and clinical characterization of extraintestinal and gastrointestinal Salmonella infection. Journal of Microbiology, Epidemiology and Immunobiology 2006, No.3, P. 36-39 [english abstract] (indexed in MedLine)

Shubin F.N., Rakov A.V., Kuznetsova N.A., Maslov D.V., Ananjev V.Yu. Structure of Salmonella enteritidis population in Primorye Region on the plasmid analysis data. Journal of Microbiology, Epidemiology and Immunobiology 2006, No. 3, P. 28-32 [english abstract] (indexed in MedLine)

Kuznetsova N.A., Shubin F.N., Rakov A.V., Tarasenko T.T., Grebenkova L.K. Intraannual dynamics of Salmonella infection caused by heterogeneous Salmonella enteritidis population. Journal of Microbiology, Epidemiology and Immunobiology 2006, No. 3, P. 32-36 [english abstract] (indexed in MedLine)

Rakov A.V., Shubin F.N. Salmonella enteritidis infection caused by strains not containing virulence plasmid. Abstracts of 2nd ASM Conference on Salmonella. Canada, 2006. P. 61-62.[PDF] (684 kb)

Shubin F.N., Rakov A.V., Kuznetsova N.A. Molecular epidemiology of Salmonella enteritidis infection in Siberia and Far East of Russia. Abstracts of 2nd ASM Conference on Salmonella. Canada, 2006. P. 75.[PDF] (684 kb)

Rakov A.V., Shubin F.N. Genetically marked Salmonella enteritidis populations in northern regions of the Far-East of Russia. Abstracts of the 13th International Congress on Infectious Diseases. June 19-22, 2008. Kuala Lumpur, Malaysia, 2008. P. 81.[PDF] (32 kb)

Rakov A.V., Shubin F.N. Epidemiogical features of morbidity caused by imported Salmonella enteritidis plasmid types in Primorye Territory. Abstracts of 3rd ASM Conference on Salmonella: Biology, Pathogenesis & Prevention. October 5-9, 2009. Aix-en-Provence, France, 2009. P. 31-32.[PDF] (1.56 Mb)

Rakov A.V., Shubin F.N., Kuznetsova N.A. Features of infection caused by Salmonella enteritidis not containing virulence plasmid. Epidemiology and Infectious Diseases (Moscow) 2010, No. 2, P. 31-33. [english abstract] [russian abstract] (indexed in Ulrich's International Periodical Directory)

Rakov A.V., Ubukata K., Robinson D.A. Population structure of hyperinvasive serotype 12F, clonal complex 218 Streptococcus pneumoniae revealed by multilocus boxB sequence typing. Infect. Genet. Evol. 2011, Vol. 11, No. 8, P. 1929-1939. doi:10.1016/j.meegid.2011.08.016.[abstract] (indexed in PubMed/Medline)

Zulz T., Wenger J.D., Rudolph K., Robinson D.A., Rakov A.V., Bruden D., Bruce M.G., Hennessy T. Streptococcus pneumoniae serotype 12F in Alaska: Epidemiology and report of a rural community outbreak. Clin. Infect. Dis. 2012. Manuscript in preparation.

Rakov A.V., LeRoy C.E., Smyth D.S., Luo X., Dagan R., Rudolph K.M., Robinson D.A. Tn6078: A novel mobile genetic element discovered in pneumococcal outbreak strains has geography-specific invasive disease associations. 2013. Manuscript in preparation.

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